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Traversing barriers. Bridging solutions. Changing lives.

Our Story

A brilliant biochemist and veteran of the biotechnology industry, Dr. Ram Bhatt left his homeland at a young age to pursue an education with hopes of one day solving the problem of the blood brain barrier. 35 years of scientific and executive experience in the biotechnology industry later, Dr. Bhatt started his own company to tackle the challenge in 2008. Just three years later, Dr. Bhatt and his team had proven the principle that a molecule directed to a target could enter and pass through the Blood Brain Barrier, unlocking a new frontier in the treatment of neurodegenerative disorders.

Our Mission

To design and develop innovative technologies capable of optimizing, cloning and mass production. We are committed to aiding in the fight against major diseases faced by humans all around the world today

Our Science

Our SMART Molecule Technology Platform (Specific Molecular Architecture for Recognition and Therapy) is a stripped down antibody mimic capable of identifying and eradicating any disease that leaves a target protein in the body.

Our Impact

Our current focus is on Parkinson’s and Alzheimer’s due to our desire to demonstrate our ability to penetrate the blood brain barrier. Proving our ability to do so now points at our ability to get through any tissue in the body, and bring Smart Molecules with low bulk and high target specificity to fight against virtually any major disease in the human body.

The Innovative California Biosciences International (ICBI) Team

Dr. Ram Bhatt, Ph.D.

Chairman, Chief Executive Officer and Founder ICBI

Dr. Ranya Alexander, Ph.D., MD

Chief Operating Officer

Douglas Bennett, MBA

Vice President, Investor Relations

Dr. Arvind Bhambri, Ph.D.

Strategy Officer

Advisory Team

Dr. Robert Y. Ning, Ph.D., MBA

Dr. Robert Y. Ning, Ph.D., MBA


Dr. Ning has worked in the pharmaceutical industry for over 25 years, most recently as Vice President of Science and Business Development, and has published numerous papers on organic and process chemistry.

Dr. Anna Cartier, Ph.D.

Dr. Anna Cartier, Ph.D.


Dr. Jayaraman A. Rao, MD

Dr. Jayaraman A. Rao, MD


Jo Rosen


As the former President and CEO of R J Romero Financial Management Services, Inc., Ms. Rosen brings with her an abundance of business and financial management skills that have been very successful. Managing and overseeing the management of a multitude of clients, Ms. Rosen skillfully turned clients in crisis into clients of means. With her near three decades of experience as President and Executive Director of Parkinson’s Resource Organization, Ms. Rosen personally met the challenges of Parkinson’s with her late mother and her late husband. Her breadth of knowledge about the disease, living with the disease with the greatest quality of life, and the science that has been pervading the Parkinson’s world for these decades is equal to the ICBII dedication and determination to bring the reversal of Parkinson’s to this world.

Latest Press

September 22, 2021 in Press Releases

ICBII Announces Approval of Its 7th Patent on Blood-Brain Barrier Permeable Technology, Moving Closer to Clinical Trials on its drugs for Alzheimer’s, Parkinson’s, and Other Neuro-Degenerative Diseases

NEWS PROVIDED BY Innovative California Biosciences International, Inc.  Sep 22, 2021, 20:26 ET LA JOLLA, Calif., Sept. 22, 2021 /PRNewswire/ -- Innovative California Biosciences International, Inc., ("ICBII"), has announced the approval of…
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March 29, 2019 in Press Releases

2019 Market Report: Novel Technologies for Delivery of Proteins, Antibodies and Nucleic Acids, 2019-2030

ICBII Interview Transcript-Chapter 12.3.2 and Globe Newswire, March 29, 2019 Ram Bhatt CEO, Chairman and Founder ICB International Roots Analysis: Can you tell us about ICB International? ICB International,…
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December 18, 2018 in Press Releases

ICBII announces approval of two US patents and filing of two divisional patent applications in Europe.

La Jolla, California, USA, Innovative California Biosciences International, Inc., (“ICBII”), announced on December 21, 2018 that the US Patent Office granted two of its patents, making the total approved number…
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ICBI Neurodegenerative Pipeline

We are in preclinical studies for Parkinson’s disease and Alzheimer’s disease. As a platform technology, we intend to pursue studies where we believe our SMART molecules can address other debilitating diseases including brain cancer, colon cancer, breast cancer and prostate cancer.

IP Portfolio

Approved Patents

  1. Methods for using antibodies and analogs thereof: EP 2350655
  2. Blood-brain barrier permeable peptide compositions: EP 13000098.7
  3. Blood-brain barrier permeable peptide compositions: US 13/917,010
  4. Blood-brain barrier permeable peptide compositions: US 13/736,852
  5. Blood-brain barrier permeable peptide compositions: EP 13171872.8


  1. Methods for using antibodies and analogs thereof: US12/606,808
  2. Antibodies, analogs, and uses thereof: US 12/563,330
  3. Methods for using antibodies and analogs thereof: EP 09825245.5
  4. Methods for using antibodies and analogs thereof: EP: 16204570.2
  5. Blood-brain barrier permeable peptide compositions: EP 17187006.6


Molecular Imaging Insights into Neurodegeneration: Focus on α-Synuclein Radiotracers, Maliha Shah, John Seibyl, Anna Cartier, Ram Bhatt and Ana M. Catafau, J Nucl Med. 2014:55:1397-1400.